Therapeutic Targets Database

Some of the useful information about the known and unknown protein as well as the target for nucleic acid can be determined using a database called as Therapeutic Target Database. On top of that, with the use of this database, the targeted disease, information about the mechanism of the disease can be identified .

In this example, I am using the alzheimer's disease as the example.

There are some drug targets in which the drugs can act specifically to such as Acetylcholinesterase, NMDA receptor and many more. For example, Tacrine and Galantamine can act on the Acetylcholinesterase, Memantine can act on NMDA receptor. 

There are different levels of alzheimer's disease such as mild to moderate alzheimer's disease,cognitive impairment associated with the alzheimer's disease and tauopathies. In the mild to moderate alzheimer's disease, the drug targerts are amyloid beta and the drugs such as BAN2401 and UB-311 can act specifically to the drug target. In the cognitive impairment associated with the alzheimer's disease, 5-HT4 is the drug target in which the TD-8954 can act on this target drug. In the tauopathies, microtubule is the drug target in which the BMS-241027 can act specifically on a specific drug target. 

With the aid of this database, scientist can determine a specific drug target easily. if any disease occurs, scientist can cure a certain disease by focusing on the drug target and determine which drug that is useful and can act specifically to the drug target.